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mineralocorticoid receptor antagonists Introduction Psoriasi
2018-10-25
Introduction Psoriasis is a common chronic inflammatory disease with different clinical presentations. The prevalence of psoriasis is about 2–3% in the general population. Its etiology is not yet well understood. Although it is known as a T lymphocyte mediated disease, various inflammatory cell typ
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Uno de los trabajos pioneros sobre
2018-10-25
Uno de los trabajos pioneros sobre rock y mujeres es el de , el cual visibiliza desde una crítica feminista cómo el fenómeno rockero presenta asimetrías entre mujeres y hombres sostenidas por símbolos masculinos que hacen del rock un (rock fálico). Dichas asimetrías se muestran cuando las mujeres,
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El segundo argumento de Young esgrime que
2018-10-25
El segundo argumento de Young esgrime que los agentes pueden participar de injusticias estructurales sin que podamos asignarles culpa alguna. Este argumento es débil, ya que los ciudadanos tienen la tarea de vigilar el buen funcionamiento de las instituciones y de rastrear cuando las injusticias son
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Hay otros aspectos de la tica feminista que deber an
2018-10-25
Hay otros aspectos de la ética feminista que deberían transferirse MG132 la bioética, incluidos los desafíos hechos por las feministas a algunos conceptos clave de la ética tradicional. Por ejemplo, las feministas han cuestionado la utilidad del concepto del individuo abstracto como unidad moral y s
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Muchas feministas coincidieron con Barry en su planteamiento
2018-10-25
Muchas feministas coincidieron con Barry en su planteamiento en Esclavitud sexual de la mujer (1979), donde sostiene que los valores que las mujeres siempre le han atribuido CT99021 la sexualidad habían sido distorsionados y destruidos conforme habían sido “colonizadas” a través tanto de la violenci
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Es en este contexto donde adquiere sentido la
2018-10-25
Es en este contexto donde adquiere sentido la frase: “yo puedo tener hijos normales”, que enunció la pareja de Mónica cuando la abandonó abacavir ella y a su hija con síndrome de Down. Como señala De Lauretis (1987), el género es tanto una construcción sociocultural como un aparato semiótico, un sis
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To develop an effective cell based
2018-10-24
To develop an effective cell-based therapy against neurodegenerative disorders of the CNS, efficient recruitment of the cells into the CNS is essential. Previous findings suggest that particular bone marrow derived cells are able to cross the blood–brain barrier (Lebson et al., 2010; Simard and Rive
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The expansion and maturation of mature ECs and
2018-10-24
The expansion and maturation of mature ECs and EPCs requires the addition of pro-angiogenic growth factors such as VEGF. With regards the translation of cell-based therapies into clinic, it is of interest to avoid the expensive and controversial use of recombinant growth factors. The supplementation
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Experiments in NHPs can also be more technically challenging
2018-10-24
Experiments in NHPs can also be more technically challenging than those carried out in rodents. For example, MPTP is a highly toxic reagent and animals exposed to it need to be housed in biosafety level 2 laboratories and cared for by highly trained staff. Further, although a stereotactic atlas does
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br Materials and methods br Author disclosure statement
2018-10-24
Materials and methods Author disclosure statement Acknowledgments This work was supported by the National Institutes of Health K08 grant number HL111148 (J.L.S.) and R01 grant number HL051387 (D.E.V.). We are especially indebted to patients and their families for participating in this study
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br Results Relying on the high
2018-10-24
Results Relying on the high conservation of vertebrate TBX3 proteins, we used human TBX3 in murine ESCs due to its specific traceability. We inserted human TBX3 cDNA into the pEF-DEST51 vector (Invitrogen) for EF1α-promoter-based stable and constitutive overexpression in ESCs. Out of 20 independe
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br Experimental Procedures br Acknowledgments br Introductio
2018-10-24
Experimental Procedures Acknowledgments Introduction Hepatitis C virus (HCV) infects an estimated 2%–3% of the world population and is a major cause of liver disease and cancer. It is estimated that more than 350,000 people die of the HCV-related liver disease each year (Te and Jensen, 2010
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We propose that a quantitative marker
2018-10-24
We propose that a quantitative marker for tracking cardiac myocyte maturation resides in the developmentally controlled and irreversible (excepting targeted reprogramming) genetic switch in the sarcomeric TNNI gene. Owing to strict developmental control in all mammalian hearts, including humans, the
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It is intriguing that all surviving germ cells
2018-10-24
It is intriguing that all surviving germ cells in Ret mutant mice expressed GFRA1. It is possible that GFRA1 was upregulated to compensate for the reduction of GDNF signaling. Because of the controversy on GFRA1 expression on SSCs, we performed FACS experiments to explore the relationship between GF
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Since the donor hESC derived cells are allografts
2018-10-24
Since the donor hESC-derived melanotropin are allografts, there is the possibility of graft rejection after transplantation. Previous allogeneic RPE cell transplantations in dry AMD resulted in graft rejections in some cases, although it started later in the treatment course and was seen less freque
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