• br Antimicrobial drugs are the most counterfeit or

  2019-06-29

  

  Antimicrobial drugs are the most counterfeit or substandard drugs worldwide. The pharmacopoeial quality of these drugs in China is of special concern because China is the second producer, after India, of most counterfeit or substandard drugs in the global market. The antimicrobials circulating in

• Conflicts of interest br Introduction

  2019-06-29

  

  Conflicts of interest Introduction Hepatocellular carcinoma (HCC) is one of the most common cancers and is the second leading cause of cancer death worldwide. In 2012, 782,500 new HCC cases and 745,500 deaths were caused by this persistent disease worldwide, with about 50% of the total number of

• Heart failure is a complex disease and the status

  2019-06-29

  

  Heart failure is a complex disease and the status of each patient is highly heterogeneous; therefore, nominal manufacturer-delivered device settings may not be optimal for all patients who receive CRT implantation. A growing body of evidence suggests hemodynamic and clinical status benefits associat

• The results described thus far suggest that

  2019-06-29

  

  The results described thus far suggest that PtAF-induced atrial remodeling combined with acute atrial stretch facilitates anchoring of 3-D scroll waves to the border of atrial pectinate muscle and prolongs their life span in favor of AF maintenance. However, why is it that scroll waves anchor to the

• Surgery especially modified radical mastectomy is

  2019-06-29

  

  Surgery, especially modified radical mastectomy, is the “gold standard” for the treatment of male breast cancer. Postoperative adjuvant radiotherapy is recommended for male patients with large breast cancer and axillary lymph node and chest muscle involvement; it can reduce the risk of local cancer

• Patients with syncope often suffer

  2019-06-29

  

  Patients with syncope often suffer secondary trauma. Major morbidities such as fractures and injuries from motor vehicle accidents have been reported in 6% of patients, whereas minor injuries such as lacerations and bruises have been reported in 29% [1]. Recurrent syncope was associated with fractur

• br Clinical characteristics Brugada syndrome is

  2019-06-29

  

  Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn

• br Discussion We successfully prevented the initiation

  2019-06-29

  

  Discussion We successfully prevented the initiation of AF without inhibiting the AF-triggering APB, and eliminated the AF-triggering APB located close to the sinus node without damage to sinus node function. Nifekalant is an IKr antagonist that prolongs the duration of myocardial GX-674 and preve

• Bisphosphonates are the cornerstone of management in postmen

  2019-06-29

  

  Bisphosphonates are the cornerstone of management in postmenopausal osteoporosis with randomised trial evidence of reductions in vertebral fractures for ibandronate [15] and both vertebral and non-vertebral fracture rates for alendronate [16], risedronate [17], and zoledronic EI1 [18]. Ibandronate

• Introduction Catheter ablation of accessory pathways

  2019-06-29

  

  Introduction Catheter ablation of accessory pathways (APs) can be challenging depending on the location of the AP. Anteroseptal APs are rare but associated with lower success rates and higher incidence of atrioventricular (AV) block [1,2]. Data regarding the electrocardiographic and electrophysiolo

• In addition our present findings demonstrated that NOACs

  2019-06-29

  

  In addition, our present findings demonstrated that NOACs may offer advantages over warfarin therapy besides efficiency and safety. The time to ECV in the present OAC-naïve patients was significantly shorter in the NOAC group compared to the VKA group. This may be explained by the delayed achievemen

• Adem s las situaciones en

  2019-06-29

  

  Además, las situaciones en las que Nicolás se encuentra con las piedras, sus dudas en torno dna ligase si son piedras-huesos o simples piedras, sus caminatas por cerros, encrucijadas y pueblos más o menos fantasmales, las respuestas diferentes a sus preguntas por Pedro Páramo (“¿se acuerda que yo qu

• Desde esta ptica Jim nez opina que

  2019-06-29

  

  Desde esta óptica, Jiménez opina que el , como pocos artistas de su momento, “sabía que el país se encontraba tironeado entre los afanes de modernización política y cultural de sus élites y el rezago económico y social de su inmensa mayoría”, panorama nada ajeno cholecystokinin receptor más de un si

• Seg n Patricia Fagen en su estudio

  2019-06-29

  

  Según Patricia Fagen, en su estudio clásico sobre el exilio español, “un numero sorprendente de jóvenes participaron en el Movimiento 1959 y muchos más hubieran participado si hubiesen creído que había algo significativo con lo que hubieran podido contribuir”. El espíritu de ruptura con las disputas

• The mechanism leading to the

  2019-06-29

  

  The mechanism leading to the gelatinous transformation may involve inhibition of tyrosine kinase activity by tyrosine kinase inhibitors (TKI) leading to blockage of downstream signal pathways, affecting extracellular matrix deposition, adipocyte differentiation and angiogenesis. Moreover, the catabo

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