• The first transcription factor TF known to

  2019-10-25

  

  The first transcription factor (TF) known to interact with one of the cis-acting GAREs is GAMYB protein, the expression of which is induced by GA in the aleurone BG45 synthesis of barley (HvGAMYB) (Gubler and Jacobsen, 1992). GAMYB is an important regulator of endosperm functions during seed develo

• RNA sequencing RNA seq is a particularly effective

  2019-10-25

  

  RNA-sequencing (RNA-seq) is a particularly effective technology for gene discovery in a given process, especially in non-model species for which reference genome sequences are not available. Although the major application of RNA-seq analyses is the identification of differentially expressed genes (D

• Orange spotted grouper Epinephelus coioides is a coral reef

  2019-10-25

  

  Orange-spotted grouper (Epinephelus coioides) is a coral reef fish with a high commercial value in China and Southeast Asian countries. However, in recent years, various outbreaks of viral diseases have affected the grouper aquaculture industry (Wei et al., 2010). Specifically, Singapore grouper iri

• The synthetic route of R changed derivatives is shown

  2019-10-25

  

  The synthetic route of R-changed derivatives is shown in . Compounds – were prepared from commercially available 4-nitro-1-indazole (). After same two steps with , the N-substituted indazole of was produced using the Suzuki reaction in a good yield (85%). Reduction of was performed using Pd/C, and

• br Amygdala microcircuitry and fear learning Recent work

  2019-10-25

  

  Amygdala microcircuitry and fear learning Recent work has begun to dissect functional amygdala circuits that are responsible for the acquisition and expression of fear learning. Ciocchi et al. (2010) identified separable populations of 3-Deazaadenosine within the CeAL that have opposite responses

• Pregnenolone Carbonitrile Despite the significant associatio

  2019-10-24

  

  Despite the significant associations between TNF-α and TRAIL in our results, the use of a single top cytokine in predicting sPTB is limited, and the previous study using the specific candidate cytokines failed to accurately predict the risk for sPTB in asymptomatic women, with AUC ranged from 0.48 t

• Previous studies from our laboratory have demonstrated that

  2019-10-24

  

  Previous studies from our laboratory have demonstrated that CysLT1R mRNA and protein expression can be upregulated by T2-type cytokines (IL-13, IL-4, and IL-5) in monocytes, macrophages, and eosinophilic HL-60 cells., To our knowledge, however, there are no studies on interactions of cytokines (suc

• Among the CYP enzymes CYP D has been considered a

  2019-10-24

  

  Among the CYP450 enzymes, CYP2D has been considered a crucial protein that involves in the metabolism of xenobiotics and drugs (Zanger and Schwab, 2013). Some isoforms of the CYP2D subfamily have been well characterized, such as CYP2D6 due to its clinical importance and CYP2D14 in black cattle (Hama

• To the best of our knowledge

  2019-10-24

  

  To the best of our knowledge, this study was the first to demonstrate in vitro and in vivo that the lipolytic effect of kinsenoside results from coordination between PKA and AMPK pathways. We validated the lipolytic effect of kinsenoside in vivo and the effect of PKA activation on the modulating AMP

• DNA methylation is a relatively stable but reversible epigen

  2019-10-24

  

  DNA methylation is a relatively stable but reversible epigenetic mechanism that can regulate gene expression, and occurs at the three different cytosine sequence contexts (CG, CHG, and CHH, where H is C, A, or T) in plants [15]. Many studies suggest that DNA methylation status of genes influence pla

• Finally the effect of the BMIM

  2019-10-24

  

  Finally, the effect of the [BMIM][BF4] concentration change on the P-T diagram of methane hydrate was predicted using the proposed model. Three various concentrations (including 10%, 15% and 20%) were considered for calculations. The experimental data [49] and modeling results are demonstrated and c

• With regards to what might represent a typical baseline ChE

  2019-10-24

  

  With regards to what might represent a typical “baseline” ChE (or AChE) activity in Saccostrea sp., it Bufalin should be remembered that the observed enzyme responses were obtained in laboratory exposures, over a narrow experimental window (96h), with specimens collected over the course of a week,

• Prenylation may turn a flavonoid from an

  2019-10-24

  

  Prenylation may turn a flavonoid from an agonist to an antagonist and improve the selectivity to both ERs depending on the position of the substitution. C-8 prenylation appears to promote antagonism to a larger extent than C-6 in ERα due to steric hindrance against generation of agonistic conformati

• Although it is well established that estrogen and ESR

  2019-10-24

  

  Although it is well established that estrogen and ESR1 mediate numerous reproductive processes, increasing evidence suggests that ESR2 also lays an integral role in reproduction. ESR2 is a mediator in folliculogenesis and may also act by stimulating ovulation and regulating luteinization (Su et al.,

• In this study we also conducted an analysis comparing

  2019-10-24

  

  In this study, we also conducted an analysis comparing the expression profiling of Hh genes among the sarcomas investigated. In these tumors, the IHH gene showed a higher expression level than PTCH1 gene in RMS and SS samples (pbetulinic Cyclo(RGDyK) in human RMS cell lines as well as mouse NIH-3T3

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