• Metabotype data coupled to metagenomic measurements informat

  2018-10-23

  

  Metabotype data coupled to metagenomic measurements (information on gut microbiota) can enhance our knowledge about the complex interactions between the host and its gut microbiota (Kaddurah-Daouk et al., 2014) as well as their role in modulating host physiology, gut microbiome-related disorders, an

• br The Role of Glucose Metabolism in HIV Pathogenesis br

  2018-10-23

  

  The Role of Glucose Metabolism in HIV Pathogenesis Metabolic Regulation of Monocytes Monocytes dramatically change their metabolic phenotype from oxidative to glycolytic metabolism when activated in humans (Dietl et al., 2010; Cramer et al., 2003), similar to what is observed in T cells. In a

• Phenformin Some of the identified signals can be attributed

  2018-10-23

  

  Some of the identified signals can be attributed to confounding by indication. This is most notable for the observed associations with lung cancers. As an example, drugs used to treat obstructive lung diseases exhibited a strong association with squamous cell carcinoma of the lung (OR, 2.61), which

• br Materials and methods br Funding source br Results br

  2018-10-23

  

  Materials and methods Funding source Results Discussion In this study, we report a global evaluation of the state of activation of the immune, endothelial and coagulation systems in 120 treated patients aviremic for at least 2years. A first conclusion is that these patients overall prese

• Histidine rich glycoprotein HRG is a kDa plasma glycoprotein

  2018-10-23

  

  Histidine-rich glycoprotein (HRG) is a 75kDa plasma glycoprotein produced in and secreted from the liver (Koide et al., 1986). The plasma levels of HRG in healthy human were reported to be constant around 1μM (Poon et al., 2011). HRG\'s primary amino monooxygenase sequence has an extraordinary numb

• br Funding Sources br Role of

  2018-10-23

  

  Funding Sources Role of Funding Source Conflicts of Interests Author contributions Introduction The effect of disease modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis (RA) on disease activity is generally presented using population means (Combe et al., 2015; Gabay et al.

• br Genetics of Pain Sensitivity Pain is

  2018-10-23

  

  Genetics of Pain Sensitivity Pain is a distressing feeling often caused by unpleasant stimulation resulting in tissue damage, and is the most common reason for general practitioner consultations in the developed world. Geoff Woods (Cambridge, UK) presented the latest developments in the study of

• The utility of newborn TSH

  2018-10-23

  

  The utility of newborn TSH and 17-OHP levels in addition to Hb ratios in model performance was also explored. Similar to hemoglobin, TSH and 17-OHP offer practical advantages as they may be routinely obtained by fluorometric or colorimetric assay rather than by mass spectrometry analysis. These anal

• Infections with eleven species of pathogens associated with

  2018-10-23

  

  Infections with eleven species of pathogens associated with cancers are classified as Group 1 carcinogens, definitely “carcinogenic to humans”, by the IARC. These agents include Helicobacter pylori, hepatitis B virus (HBV), hepatitis C virus (HCV), Opisthorchis viverrini, Clonorchis sinensis, Schist

• Treating Age related Macular Degeneration Using Human iPS Ce

  2018-10-23

  

  Treating Age-related Macular Degeneration Using Human iPS Cells Age-related macular degeneration (AMD) is a medical condition of the eye that results in blurred vision and/or a loss of central vision. The wet form of AMD – caused by abnormal blood vessel growth – is often treated using anti-VEGF me

• br Introduction Oral Oropharyngeal mucositis

  2018-10-23

  

  Introduction Oral/Oropharyngeal mucositis (OM) is probably the most common and debilitating complication that can occur during and shortly after radiotherapy and/or chemotherapy for patients with head-and-neck cancer (HNC). It is typically characterized by: erythema, edema, mucosal ulceration and

• br Conflict of Interest Statement br Author

  2018-10-23

  

  Conflict of Interest Statement Author Contributions N.M., K.N., M.G., R.J.O., and M.K. performed in vitro and in vivo experiments; N.M., H.D., and M.K., performed protein purification, crystallization, data collection, structure determination, and structural analyses; P.C., and J.D.H. carried

• These last few years have seen a shift in

  2018-10-23

  

  These last few years have seen a shift in emphasis from the investigation of individual age-related diseases in isolation toward a broader context to define the basic biology of aging. The concept behind the recently coined pursuit of GeroScience (Burch et al., 2014) is that a strategy to delay the

• Recently several supervised learning methods such as

  2018-10-23

  

  Recently, several supervised learning methods, such as decision trees, have been applied to the analysis of cDNA microarrays to refine prognosis in nasopharyngeal carcinoma, breast cancer and non–small-cell lung cancer.(Chen et al., 2007) State-of-the-art classification algorithms such as support ve

• Reagents Anti HO antibody was purchased

  2018-10-23

  

  Reagents Anti-HO-1 antibody was purchased from Assay Design and R&D systems respectively. Anti-β-actin antibody, heme (hemin) and desferoxamine (DFO), were obtained from Sigma-Aldrich. Hemopexin deficient (HPX−) serum was a kind gift from Dr. EmanualaTolosano, Molecular Biotechnology Center, Univer

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